References

  1. Borgstrom L, Kagedal B, Paulsen O Pharmacokinetics of NAS in man. Eur. J. Clin. Pharmacol 1986; 31: 217-222
  2. Olivieri D. et.al. Improvement of mucociliary transport in smokers by mucolytics. Eur. J. Respir. Dis. 66 (Suppl. 139): 142-145, 1985
  3. Brocard H. et. Al. Acute indications for Acetylcysteine – Etude multi-centrique en double aveugle avee acetylcysteine orale vs placebo. Eur. J. Resp. Dis. 61 (Suppl. 111); 65-69, 1980
  4. Kasielski M et. al. Long-term administration of N-acetylcysteine decreases hydrogen peroxide exalation in subjects with chronic obstructive pulmonary disease. Resp. Med. 95: 448-456, 2001
  5. Briedgeman M.M. et.al. Cysteine and gluthathione concentrations in plasma and bronchoalveolar lavage fluid after treatment with N-acetylcysteine. Thorax 46: 39-42, 1991
  6. Gerrits C. M. J. M. et. Al. N-acetylcysteine reduces the risk of re-hospitalization among patients with chronic obstructive pulmonary disease. Eur. Respir. J.21: 795-798, 2003
  7. Stey C et. Al. The effect of oral N-acetylcysteine in chronic bronchitis: a quantitative systematic review.
  8. Zuin P. et. Al. High-dose N-acetylcysteine in patients with exacerbation of chronic obstructive pulmonary disease. Clin. Drug invest: 25: 401-408, 2005.
  9. www.fluimucil.it/en/History
  10. https://en.wikipedia.org/wiki/Acetycysteine
  11. Zheng JP et.al. Twice daily N-acetylcysteine 600mg for exacerbations of chronic obstructive pulmonary disease (PANTHEON): a randomized, double-blind placebo-controlled trial. Lancet Respir Med 2014;2:187-94
  12. http://upgradetestfluimucil.icsadv.com/en-us/
  13. https://en.wikipedia.org/wiki/Bronchitis
  14. https://www.nhs.uk/conditions/bronchitis/
  15. https://www.nhlbi.nih.gov/health-topics/bronchitis
  16. https://www.healthline.com/health/copd/understanding-chronic-bronchitis
  17. Hoi Nam Tse et. al. High-dose N-acetylcysteine in stable COPD: The 1-Year, Double-Blind, Randomized, Placebo-Controlled HIACE Study. CHEST 2013;144(1):106-118
  18. Jan De Backer et. al. Effect of high-dose N-acetylcysteine on airway geometry, inflammation, and oxidative stress in COPD patients. International Journal of COPD 2013:8 569-579

References

  1. Borgstrom L, Kagedal B, Paulsen O Pharmacokinetics of NAS in man. Eur. J. Clin. Pharmacol 1986; 31: 217-222
  2. Olivieri D. et.al. Improvement of mucociliary transport in smokers by mucolytics. Eur. J. Respir. Dis. 66 (Suppl. 139): 142-145, 1985
  3. Brocard H. et. Al. Acute indications for Acetylcysteine – Etude multi-centrique en double aveugle avee acetylcysteine orale vs placebo. Eur. J. Resp. Dis. 61 (Suppl. 111); 65-69, 1980
  4. Kasielski M et. al. Long-term administration of N-acetylcysteine decreases hydrogen peroxide exalation in subjects with chronic obstructive pulmonary disease. Resp. Med. 95: 448-456, 2001
  5. Briedgeman M.M. et.al. Cysteine and gluthathione concentrations in plasma and bronchoalveolar lavage fluid after treatment with N-acetylcysteine. Thorax 46: 39-42, 1991
  6. Gerrits C. M. J. M. et. Al. N-acetylcysteine reduces the risk of re-hospitalization among patients with chronic obstructive pulmonary disease. Eur. Respir. J.21: 795-798, 2003
  7. Stey C et. Al. The effect of oral N-acetylcysteine in chronic bronchitis: a quantitative systematic review.
  8. Zuin P. et. Al. High-dose N-acetylcysteine in patients with exacerbation of chronic obstructive pulmonary disease. Clin. Drug invest: 25: 401-408, 2005.
  9. www.fluimucil.it/en/History
  10. https://en.wikipedia.org/wiki/Acetycysteine
  11. Zheng JP et.al. Twice daily N-acetylcysteine 600mg for exacerbations of chronic obstructive pulmonary disease (PANTHEON): a randomized, double-blind placebo-controlled trial. Lancet Respir Med 2014;2:187-94
  12. http://upgradetestfluimucil.icsadv.com/en-us/
  13. https://en.wikipedia.org/wiki/Bronchitis
  14. https://www.nhs.uk/conditions/bronchitis/
  15. https://www.nhlbi.nih.gov/health-topics/bronchitis
  16. https://www.healthline.com/health/copd/understanding-chronic-bronchitis
  17. Hoi Nam Tse et. al. High-dose N-acetylcysteine in stable COPD: The 1-Year, Double-Blind, Randomized, Placebo-Controlled HIACE Study. CHEST 2013;144(1):106-118
  18. Jan De Backer et. al. Effect of high-dose N-acetylcysteine on airway geometry, inflammation, and oxidative stress in COPD patients. International Journal of COPD 2013:8 569-579